Ongoing Clinical Trials

Clinical trial starting in January 2013:

Evaluation of the effects of two natural supplements (fruitflow and resveratrol) on memory: association with changes in cerebral blood flow and fitness

In this study, we are planning to evaluate the effects of two natural supplements on cognitive function and blood flow to the brain in persons with memory complaints. Fruitflow is a tomato extract component which has been shown to modify platelet activity in the vascular system and may have beneficial effects on systemic blood flow. This effect of Fruitflow is similar to aspirin which has antiplatelet activity and is used for a long time for secondary prevention of cardiovascular and cerebrovascular events in patients. In this study, our goal is to find out whether fruitflow has any beneficial effects on blood flow to the brain and thereby improving memory problems. We also evaluate effects of another natural supplement, Resveratrol, on cognitive functions, blood flow to the brain and fitness alone or in combination with Fruitflow. Resveratrol is a natural compound found in the skin of red grapes and also in wine.

           Fruitflow is a tomato extract.                                              Resveratrol is a grape extract.

The general inclusion criteria for this trial include:

• Age between 50-80
• Subjective complaint of some degree of decline in memory
• Being in stable overall health

Study Procedures:

• Initial Screening and Blood Test
• Assessment of Memory and Cognition with Several Psychological Tests
• Brain Blood Flow Measurement with Ultrasound
• Fitness Testing with a Stationary-bike

Duration:

• Three Months (90 Days)

Compensation:

The results of the study will potentially provide a new insight that Fruitflow and Resveratrol can be beneficial for improvement of brain blood flow, cardiovascular function, and memory in middle-aged and elderly individuals with memory problems.

For a downloadable version, please click here.

Clinical trials starting in 2013:

1. Role of increased fitness in improving memory and increasing brain size.
2. Role of improved sleep and treating obstructive sleep apnea in improving memory and increasing brain size.
3. Role of meditation and neurofeedback in improving memory and increasing brain size.
4. Role of cognitive therapy and memory enhancement for treating mild to moderate memory loss.
5. Role of Remviva (a neuroprotective supplement) in improving memory and increasing brain size.
6. Role of Exelon (a medication for patients with Alzheimer’s disease) in improving memory in people with mild to moderate memory loss (without Alzheimer’s disease).
7. Role of Oxygen Therapy in improving memory and increasing brain size.

The general inclusion criteria for these trials include:

• Age between 50-80
• Subjective complaint of some degree of decline in memory
• Having a family member diagnosed with Alzheimer’s disease

Details of individual clinical trials will become available soon. In general, each trial involves:

• Initial assessment and evaluation process may include: 
• Memory Testing
• Fitness Testing 
• Blood Tests
• Sleep Evaluation
• Three month check-ups over a 9-month duration of the study
• Stipend for participation and completion of the study

* If you're interested in participating in any of the clinical trials, please call our office at 410-494-0191 to reserve a spot.